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KMID : 0371420211010060340
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Annals of Surgical Treatment and Research
2021 Volume.101 No. 6 p.340 ~ p.349
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Predictive factors of high comprehensive complication index in colorectal cancer patients using Enhanced Recovery After Surgery protocol: role as a safety net in early discharge
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Jin Hyeong-Yong
Hong In-Jae
Bae Jung-Hoon
Lee Chul-Seung
Han Seung-Rim
Lee Yoon-Suk
Lee In-Kyu
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Abstract
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Purpose: This study was performed to evaluate complications using comprehensive complication index (CCI) in colorectal cancer patients with implementation of the Enhanced Recovery After Surgery (ERAS) protocol, and to investigate the predictive factors associated with high morbidity rates. It can be used as a safety net in determining the timing of discharge.
Methods: A total of 335 consecutive patients who underwent elective colorectal cancer surgery between January 2017 and December 2017 at a single tertiary center were enrolled. Postoperative complications were defined as occurring within 30 days after surgery. The predictive factor analysis for the high CCI group was also performed.
Results: In total, 116 patients experienced postoperative complications. Wound-related complications and postoperative ileus were the most common. The mean CCI for overall colorectal cancer surgery was 9.1 ± 16.7. Patients featuring low CCI (<26.2) were 297 (88.7%) and high CCI were 38 (11.3%). In multivariable analysis, obstructive colorectal cancer (odds ratio, 3.278; 95% confidence interval, 1.217?8.829; P = 0.019) and CRP value on postoperative day (POD) 3?4 (odds ratio, 1.152; 95% confidence interval, 1.036?1.280; P < 0.010) were significant predictors for high CCI.
Conclusion: The clinical usefulness of CCI in colorectal cancer patients with the ERAS protocol was verified, and it can be used for surgical quality control. More cautious care is needed and the timing of discharge should be carefully determined for patients with obstructive colorectal cancer or POD 3?4 CRP of ≥6.47 mg/dL.
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KEYWORD
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Colorectal neoplasms, Comprehensive complication index, C-Reactive protein, Enhanced Recovery After Surgery, Postoperative complications
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